2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(7-methyl-1H-indol-3-yl)propanoic acid - Names and Identifiers
2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(7-methyl-1H-indol-3-yl)propanoic acid - Physico-chemical Properties
Molecular Formula | C27H24N2O4
|
Molar Mass | 440.49 |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD02682379 |
2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(7-methyl-1H-indol-3-yl)propanoic acid - Risk and Safety
2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(7-methyl-1H-indol-3-yl)propanoic acid - Introduction
Fmoc-7-methyl-DL-tryptophan is a compound that has the following properties:
1. Appearance: A white to light yellow crystalline solid.
2. molecular formula: C33H28N2O4.
3. Molecular weight: 520.59g/mol.
4. Solubility: Soluble in organic solvents (such as methanol, dimethyl sulfoxide), insoluble in water.
5. Melting point: about 136-139°C.
6. storage conditions: to be stored in a dry, dark and low temperature environment.
Fmoc-7-methyl-DL-tryptophan are commonly used in chemical and biological research and have the following uses:
1. Protein synthesis: It can be used as an amino acid in synthetic peptides and proteins.
2. peptide chemistry: can be used for the synthesis of new drugs and drug molecules improved.
3. biological activity research: can be used to study the interaction of related biological processes and biomolecules.
The synthesis method of Fmoc-7-methyl-DL-tryptophan is as follows:
First, 9-fluorenecinol and formaldehyde are subjected to a condensation reaction to prepare 9H-fluorene-9-formaldehyde. Then, 9H-fluorene-9-carbaldehyde is subjected to a condensation reaction with dimethylcarbamate methyl ester to obtain 9H-fluorene-9-methoxycarbaldehyde. Next, 9H-fluorene-9-methoxycarbaldehyde was subjected to a condensation reaction with silver formic acid chloride to obtain 2-(((9H-fluoren-9-yl) methoxy) carbonyl) carboxylic acid. Thereafter, condensation reaction with indoleacetic acid methyl ester gives Fmoc-7-methyl-DL-tryptophan.
When handling this compound, you need to pay attention to the following safety information:
1. avoid contact with skin and eyes, avoid inhaling its dust or gas.
2. Preparation and operation should be carried out in a well-ventilated environment, and wear appropriate protective equipment (such as gloves, goggles, etc.).
3. If you come into contact with the compound, rinse immediately with plenty of water and seek medical advice if necessary.
Finally, it is emphasized that when using the compound, it should be operated in strict accordance with relevant safety operation procedures and follow the correct disposal methods.
Last Update:2024-04-09 22:02:01